We will post 2009 Conference Abstracts as they are submitted to us by registered attendees. If you haven't done so already, please be sure to register with us and then login to upload your abstract to the conference administrators.

Chair & Speaker Abstracts

J. MICHAEL BISHOP.
Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, 94131
The Genome and the War on Cancer

MARTIN J. BLASER.
Departments of Medicine and Microbiology, New York University Langone Medical Center, New York, NY 10016
The Upper Gastrointestinal Microbiota and Gastric and Esophageal Adenocarcinomas

George A. Calin.
Department of Experimental Therapeutics University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030
The Interplay Between MicroRNAs and Ultra-conserved RNAs in Cancer

W. K. CAVENEE
Ludwig Institute, University of California at San Diego, La Jolla, CA 92093-0660
Session 9: Epigenetics

LISA M. COUSSENS, PH.D.
Department of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Email: Lisa.Coussens@ucsf.edu
REGULATION OF PROTUMOR IMMUNITY AND BREAST CANCER DEVELOPMENT

Carlo M. Croce
M.D., The Ohio State University, Columbus, OH 43210
Session 8: Non-Coding RNA and Cancer

Chi V. Dang
Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205
MYC, MicroRNAs and Metabolic Addictions in Cancers

NANCY E. DAVIDSON
University of Pittsburgh Cancer Institute, 5150 Center Avenue, Suite 500, Pittsburgh, PA 15232
New Therapeutic Approaches to “Triple Negative” Breast Cancer

RAYMOND N. DUBOIS.
The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030
Inflammation and Cancer: Molecular Targets and Opportunities

RICHARD GAYNOR
Cancer Research, Eli Lilly and Company, Indianapolis, Indiana 46285
Chronic Inflammation and Cancer

TONA M. GILMER.
Translational Research, Cancer Research, GlaxoSmithKline, Research Triangle Park, NC 27709
Personalized Medicine

STEPHEN D. HURSTING.
Department of Nutritional Sciences, University of Texas and Department of Carcinogenesis, UT-MD Anderson Cancer Center, Austin, TX 78712.
The Human Microbiome: A Potential Target for the Prevention and Treatment of Obesity, Cancer and Other Diseases.

MONTE WINSLOW, DAVID FELDSER, NATHAN YOUNG, AND TYLER JACKS
David H. Koch Institute for Integrative Cancer Research, Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology 02139
Studying Tumor Evolution in Mouse Models of Cancer

BRUCE E. JOHNSON AND PASI JÄNNE
Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 44 Binney Street, Boston, MA 02115
Novel Therapeutic Agents Against Thoracic Malignancies

PETER A. JONES
USC/Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089
The Epigenome

Michael Karin
Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology and Pathology, UCSD School of Medicine, La Jolla, CA 92093
Control of Tumor Promotion and Metastatic Progression by Inflammatory Signaling

HEIDI H. KONG, ELIZABETH A. GRICE, MARIA L. TURNER, JULIA A. SEGRE
Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Building 10, Room 12N238, Bethesda, MD 20892
Skin Microbiota in Health and Disease

John K. Leighton
Associate Director for Pharmacology/Toxicology FDA/CDER Office of Oncology Drug Products
Nonclinical Reasons for Clinical Holds in Oncology at the FDA

LAWRENCE J. MARNETT, AARON JACOBS, ANDREW VILA, KERI TALLMAN, NED PORTER, AND DAN LIEBLER. A.B.
Hancock Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt Institute of Chemical Biology, Center in Molecular Toxicology, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville TN 37232
Chemical Biology of the Cellular Responses to Protein Modification by Oxidized Lipids

MATTHEW L. MEYERSON, GAD GETZ, WENDY WINCKLER, RAMEEN BEROUKHIM, CRAIG MERMEL, JORDI BARRETINA, BARBARA WEIR, ROEL VERHAAK, CARRIE SOUGNEZ, AND MANY OTHERS.
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115
Department of Pathology, Harvard Medical School, Boston, MA 02115
Broad Institute of Harvard and MIT, Cambridge, MA 02139
Somatic Genome Alterations in Human Cancer

Charles M. Perou,
Department of Genetics and Pathology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA
Genomic Approach to Cancer Treatment

M. CELESTE SIMON,
Howard Hughes Medical Institute, Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Abramson Family Cancer Research Institute, 456 BRB II/III, 421 Curie Boulevard, Philadelphia, PA 19104-6160
Hypoxia, HIFs, and Tumor Progression

Frank J. Slack.
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520
MicroRNAs in Cell Differentiation and Cancer

THOMAS J. SLAGA, PH.D.
Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
Session 3: Metabolism, Obesity, Aging and Cancer

MARK X. SLIWKOWSKI, TEEMU T. JUNTTILA, AND LUKAS C. AMLER.
Research Oncology, Genentech, Inc. South San Francisco, CA 94080
Targeting Activated HER2 in Solid Tumors

STEVEN R. TANNENBAUM.
Departments of Biological Engineering and Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139
The Chemistry of Nitric Oxide in Inflammation and Cancer

Craig B. Thompson
Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104
Fueling Cancer Cell Growth.

NANCY DUMONT, YONGPING G. CRAWFORD, PAUL A. REYNOLDS, MATTHEW B. WILSON, MAHVASH SIGAROUDINIA, COLLEEN A. FORDYCE, AND THEA D. TLSTY.
Department of Pathology and Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Extrinsic Programming of de novo Epigenetic Remodeling

Giorgio Trinchieri1, Zsofia Gyulai1, Rosalba Salcedo1, Yava Jones1, Lyudmila Lyack1, Robin Winkler Pickett1, Loretta Smith1, Ren Ming Dai1, Anna Mason1, Christophe Cataisson2, Stuart Yuspa2.
1Cancer and Inflammation Program, CCR, NCI, Frederick, MD 21702 and 2Laboratory of Cell Biology and Genetics, CCR, NCI, Bethesda, MD 20892.
Innate Resistance, Inflammation, and Carcinogenesis.

MATTHEW G. VANDER HEIDEN1,2,3 and LEWIS C. CANTLEY2,3.
Dana-Farber Cancer Institute, Beth-Israel Deaconess Medical Center, and Harvard Medical School. Boston, MA 02115
Regulation of Cancer Cell Metabolism by Pyruvate Kinase M2

GERALD N. WOGAN
Department of Biological Engineering, Massachusetts Institute of Technology, Room 26-009, 77 Massachusetts Avenue, Cambridge, MA 02139
Free Radicals in Cancer

Fellow Abstracts

Benjamin J. Daniel
Aged Mice do not Benefit from Regulatory T Cell Depletion as a Melanoma Treatment: Yet Another Reason It Sucks to be Old.


JAYANTA DEBNATH, REBECCA LOCK, CHRISTOPHER FUNG, NAN CHEN, AND EDUARDO SALAS.
Department of Pathology, University of California San Francisco, San Francisco, CA 94122.
ONCOGENES AND DETACHMENT-INDUCED AUTOPHAGY


NANCY DUMONT, YONGPING G. CRAWFORD, MATTHEW B. WILSON, PAUL A. REYNOLDS, MAHVASH SIGAROUDINIA, AND THEA D. TLSTY.
Department of Pathology and Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA 94143.
DNA Methylation Changes in Mammary Premalignancy


STACEY L. FOSSEY1, ALBERT T. LIAO1, JENNIFER K. MCCLEESE1, MISTY D. BEAR1, JIAYUH LIN3, 5, PUI-KAI LI4, 5, WILLIAM C. KISSEBERTH2, and CHERYL A.
ONDON1,
1 Department of Veterinary Biosciences, 2Department of Veterinary Clinical Sciences,
3 Department of Pediatrics, 4Division of Medicinal Chemistry, and the 5Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
Investigating the Role of STAT3 Activation in Human and Canine Osteosarcoma


QIAN LIU1, LISA SMEESTER1, RUI ZHAO2, JINGBO PI2 AND REBECCA C. FRY1.
(1) Department of Environmental Sciences and Engineering, University of North Carolina-Chapel Hill, Gillings School of Global Public Health, Chapel Hill, NC 27599 and (2) The Hamner Institutes of Health Sciences, 6 Davis Drive, P.O. Box 12137, Research Triangle Park, NC 27709.
Identifying Genomic Predictors of Chemotherapeutic Response

KAORI FUJITA1, ABDUL M. MONDAL1, IZUMI HORIKAWA1, GINAG H. NGUYEN1,2, KENSUKE KUMAMOTO1, JANE J. SHONE1, ELISE D. BOUMAN1, EWY A. MATHE1, AARON J. SCHETTER1, SHARON R. PINE1, HELEN JI1, BORIVOJ VOJTESEK3, JEAN-CHRISTOPHE BOURDON4, DAVID P. LANE4.5 and CURTIS C. HARRIS1
p53 isoforms, ?133p53 and p53?, are endogenous regulators of replicative cellular senescence


LUIZ C. GODOY, GERALD N. WOGAN.
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139
Protein S-nitrosation as an NO•-based anti-apoptotic mechanism in melanoma cells


JACOB JUNCO, MAGDALENA KOWALCZYK, PIOTR KOWALCZYK, OLGA TOLSTYKH, MARGARET HANAUSEK, ZGIBNIEW WALASZEK, AND THOMAS J. SLAGA.
Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229
Differential effects of promising natural source inhibitors on critical features of skin tumor promotion in SENCAR mice.


KENYA MADRIC, KIMBERLY BREVING, ROBERT MITCHELL, FRANK SLACK & AURORA ESQUELA-KERSCHER.
Eastern Virginia Medical School, Department of Microbiology and Molecular Cell Biology, Norfolk, Virginia, 23507
The Role of MiRNAs During Development and Cancer Progression


APRIL L. RISINGER AND SUSAN L. MOOBERRY.
Departments of Pharmacology and Medicine, University of Texas Health Science Center, San Antonio, TX 78229
The Taccalonolides: A New Class of Microtubule Stabilizers with a Unique Mechanism of Action


JAMES G. FOX,1,2 YAN FENG,1 ELIZABETH J. THEVE,1 DAVID B. SCHAUER,1,2 JOHN M. ESSIGMANN,2 STEVEN R. TANNENBAUM,2 STANLEY M. LEMON,3 REBECCA C. FRY2,4 AND ARLIN B. ROGERS
1Division of Comparative Medicine, 2 Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02138; 3Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555; 4School of Public Health, 5Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599
Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens


BRÍD M. RYAN1,2, SHARON R. PINE2, LYUBA VARTICOVSKI2, ANA I. ROBLES2, CURTIS C. HARRIS2.
1Cancer Prevention Fellow, Office of the Director, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892. 2Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of
Health, Bethesda, MD 20892.
In Search of Lung Cancer Stem Cells: Asymmetric Division and the Immortal Strand Hypothesis.


PETER G. SLADE, MICHELLE V. WILLIAMS, JOHN S. WISHNOK AND STEVEN R. TANNENBAUM.
Massachusetts Institute of Technology, Department of Biological Engineering, Cambridge, MA 02139
Identification of serum protein-carbonyl modifications in a mouse inflammation model


SCOTT D. SLATTERY, BILL R. BRINKLEY,ADAM T. SZAFRAN, , MICHAEL A. MANCINI, REBECCA M. HALL
Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77006
Automated high throughput microscopy-based mitotic phase analysis in the study of Aurora-C kinase function in mitosis.

Smith SM1, Salcido CD2, Carlson MD2, Hursting SD1, Varticovski L2
1Department of Nutritional Sciences, The University of Texas at Austin; Austin, TX, 2Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute; Bethesda, MD
Wnt-1 mammary tumors are enriched in CD44+/CD24- cells with cancer stem cell characteristics

DIANREN XIA, DAVID G. MENTER, AND RAYMOND N. DUBOIS
Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030
Prostaglandin E2 Induces Human Enhancer of Filamentation 1 to Promote Spreading of Colorectal Carcinoma Cells
 

PHILLIPPA C. TABERLAY, TINA B. MIRANDA, JOY C. LIN, GANGNING LIANG and PETER A. JONES.
Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Ave., Los Angeles, CA 90033.
Characterizing the effects of the Polycomb and DNA methylation silencing mechanisms on the MYOD1 promoter.